Volume 16, Issue 4 p. 769-771
Clinical/Scientific Notes

Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia Syndrome

Thomas Trottenberg MD

Thomas Trottenberg MD

Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany

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Wassilios Meissner MD

Wassilios Meissner MD

Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany

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Guy Arnold MD

Guy Arnold MD

Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany

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Karl-Max Einhaupl MD, PhD

Karl-Max Einhaupl MD, PhD

Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany

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Andreas Kupsch MD, PhD

Corresponding Author

Andreas Kupsch MD, PhD

Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany

Department of Neurology, Humboldt-University, Charité-Virchow, Augustenburger Platz 1, 13353 Berlin, GermanySearch for more papers by this author
Christian Kabus MD

Christian Kabus MD

Department of Neurology, Jewish Hospital of Berlin, Berlin, Germany

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Thomas Funk MD

Thomas Funk MD

Department of Neurosurgery, Free University of Berlin, Hindenburgdamm, Berlin, Germany

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First published: 15 June 2001
Citations: 79

A videotape accompanies this article.

Abstract

We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS. © 2001 Movement Disorder Society.