Perception of emotional speech in Parkinson's Disease
Corresponding Author
Christine Schröder MD
Department of Neurology, Medical School Hannover, Germany
Medical School Hannover, Department of Neurology, Carl-Neuberg-Str. 1, 30625 Hannover, GermanySearch for more papers by this authorJanine Möbes
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorMartin Schütze MD
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorFriedemann Szymanowski
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorWido Nager MD
Department of Neurology, Medical School Hannover, Germany
Department of Neuropsychology, Otto-von-Guericke University, Magdeburg, Germany
Search for more papers by this authorMarc Bangert
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorThomas Frank Münte MD
Department of Neuropsychology, Otto-von-Guericke University, Magdeburg, Germany
Search for more papers by this authorReinhard Dengler MD
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorCorresponding Author
Christine Schröder MD
Department of Neurology, Medical School Hannover, Germany
Medical School Hannover, Department of Neurology, Carl-Neuberg-Str. 1, 30625 Hannover, GermanySearch for more papers by this authorJanine Möbes
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorMartin Schütze MD
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorFriedemann Szymanowski
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorWido Nager MD
Department of Neurology, Medical School Hannover, Germany
Department of Neuropsychology, Otto-von-Guericke University, Magdeburg, Germany
Search for more papers by this authorMarc Bangert
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorThomas Frank Münte MD
Department of Neuropsychology, Otto-von-Guericke University, Magdeburg, Germany
Search for more papers by this authorReinhard Dengler MD
Department of Neurology, Medical School Hannover, Germany
Search for more papers by this authorAbstract
Nonmotor symptoms in Parkinson's disease (PD) involving cognition and emotionality have progressively received attention. The objective of the present study was to investigate recognition of emotional prosody in patients with PD (n = 14) in comparison to healthy control subjects (HC, n = 14). Event-related brain potentials (ERP) were recorded in a modified oddball paradigm under passive listening and active target detection instructions. Results showed a poorer performance of PD patients in classifying emotional prosody. ERP generated by emotional deviants (happy/sad) during passive listening revealed diminished amplitudes of the mismatch-related negativity for sad deviants, indicating an impairment of early preattentive processing of emotional prosody in PD. © 2006 Movement Disorder Society
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