Volume 22, Issue 11 p. 1623-1629
Research Article

Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients

Pablo Martinez-Martin PhD, MD

Pablo Martinez-Martin PhD, MD

Unit of Neuroepidemiology, National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain

Search for more papers by this author
Anthony H.V. Schapira FRCP, MD, DSc, FmedSci

Anthony H.V. Schapira FRCP, MD, DSc, FmedSci

Department of Neurosciences, Royal Free Hospital Medical School and National Hospital for Neurology, Neurosurgery, Queen Square, London, United Kingdom

Search for more papers by this author
Fabrizio Stocchi MD

Fabrizio Stocchi MD

Department of Neurology, IRCCS San Raffaele Roma, Italy

Search for more papers by this author
Kapil Sethi MD, FRCP

Kapil Sethi MD, FRCP

Medical College of Georgia, USA

Search for more papers by this author
Per Odin MD

Per Odin MD

Department of Neurology, Klinikum-Bremerhaven Reinkenheide, Germany

Search for more papers by this author
Graeme MacPhee FRCP

Graeme MacPhee FRCP

Department of Care of the Elderly/Gerontology, Southern General Hospital, Glasgow

Search for more papers by this author
Richard G. Brown PhD

Richard G. Brown PhD

Department of Psychology, Institute of Psychiatry, King's College London, London, United Kingdom

Search for more papers by this author
Yogini Naidu BSc, RGN

Yogini Naidu BSc, RGN

Department of Neurology, University Hospital Lewisham, London, United Kingdom

Search for more papers by this author
Lisa Clayton BSC

Lisa Clayton BSC

Department of Neurology, Guy's King's and St. Thomas' School of Medicine, London, United Kingdom

Search for more papers by this author
Kazuo Abe MD

Kazuo Abe MD

Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan

Search for more papers by this author
Yoshio Tsuboi MD

Yoshio Tsuboi MD

Department of Neurology, Fukuoka University, Fukuoka, Japan

Search for more papers by this author
Dough MacMahon FRCP

Dough MacMahon FRCP

Department of Medicine/Care of the Elderly, Camborne-Redruth Hospital, Redruth,Cornwall, United Kingdom

Search for more papers by this author
Paolo Barone MD

Paolo Barone MD

Department of Neurology, University of Napoli, Italy

Search for more papers by this author
Martin Rabey MD

Martin Rabey MD

Department of Neurology, Assaf Harofeh Medical Center, School of Medicine, Tel-Aviv University, Zerifin, Israel

Search for more papers by this author
Ubaldo Bonuccelli MD

Ubaldo Bonuccelli MD

Department of Neurology, University of Pisa, Pisa, Italy

Search for more papers by this author
Alison Forbes RGN

Alison Forbes RGN

Department of Clinical Neurosciences King's College Hospital, London, United Kingdom

Search for more papers by this author
Kieran Breen MRCP

Kieran Breen MRCP

Research and Development Division, The UK Parkinson's Disease Society, London, United Kingdom

Search for more papers by this author
Susanne Tluk RGN

Susanne Tluk RGN

Department of Neurology, University Hospital Lewisham, London, United Kingdom

Search for more papers by this author
C. Warren Olanow MD

C. Warren Olanow MD

Department of Neurosciences, The Mount Sinai School of Medicine, New York

Search for more papers by this author
Sue Thomas RGN

Sue Thomas RGN

Department of Nursing, Royal College of Nursing, London, United Kingdom

Search for more papers by this author
David Rye MD

David Rye MD

Department of Neurology, Emory University, Atlanta, GA

Search for more papers by this author
Annette Hand RGN, MSc

Annette Hand RGN, MSc

Department of Medicine, North Tyneside General Hospital, North Shields, United Kingdom

Search for more papers by this author
Adrian J. Williams FRCP

Adrian J. Williams FRCP

Lane-Fox Sleep Centre, St. Thomas' Hospital, London, United Kingdom

Search for more papers by this author
William Ondo MD

William Ondo MD

Department of Neurology, Baylor College of Medicine, Houston, Texas

Search for more papers by this author
K. Ray Chaudhuri MD, FRCP, DSc

Corresponding Author

K. Ray Chaudhuri MD, FRCP, DSc

Department of Clinical Neurosciences, National Parkinson Foundation Centre of Excellence, Kings College Hospital, University Hospital Lewisham, Guy's King's and St. Thomas' School of Medicine, London, United Kingdom

Movement Disorders Unit, 9th Floor Ruskin Wing, King's College Hospital, Denmark Hill, London SE5 9RS, United KingdomSearch for more papers by this author
First published: 01 June 2007
Citations: 399

Abstract

2006, there was, no single instrument (questionnaire or scale) for attempting a comprehensive assessment of the wide range of nonmotor symptoms (NMS) of Parkinson's disease (PD). The PD nonmotor group, a multidisciplinary group of experts including patient group representatives developed and validated the NMS screening questionnaire (NMSQuest) comprising 30 items. The NMSQuest is a self completed screening tool designed to draw attention to the presence of NMS. In this paper, we present the results gathered from 545 patients using the definitive version of the NMSQuest highlighting the prevalence of the wide range of NMS flagged in the NMSQuest from consecutive PD patients in an international setting. © 2007 Movement Disorder Society