A comparison of the mini mental state exam to the montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease
Cindy Zadikoff MD
Department of Neurology, Northwestern University, Parkinson's Disease and Movement Disorders Center, Chicago, Illinois
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorSusan H. Fox MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorDavid F. Tang-Wai MDCM FRCPC
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorTeri Thomsen MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorRob M.A. de Bie MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorPettarusup Wadia MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorJanis Miyasaki MD Med FRCPC
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorSarah Duff-Canning PhD., C Psych
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorAnthony E. Lang MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorCorresponding Author
Connie Marras MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Toronto Western Hospital, Morton and Gloria Shulman Movement Disorders Center, McL-7, 399 Bathurst St., Toronto, Ontario, Canada M5T 2S8Search for more papers by this authorCindy Zadikoff MD
Department of Neurology, Northwestern University, Parkinson's Disease and Movement Disorders Center, Chicago, Illinois
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorSusan H. Fox MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorDavid F. Tang-Wai MDCM FRCPC
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorTeri Thomsen MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorRob M.A. de Bie MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorPettarusup Wadia MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorJanis Miyasaki MD Med FRCPC
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorSarah Duff-Canning PhD., C Psych
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorAnthony E. Lang MD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Search for more papers by this authorCorresponding Author
Connie Marras MD, PhD
Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Toronto Western Hospital, Morton and Gloria Shulman Movement Disorders Center, McL-7, 399 Bathurst St., Toronto, Ontario, Canada M5T 2S8Search for more papers by this authorAbstract
Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7–30, 4.26) than with the MMSE(16–30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P < 0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD. © 2007 Movement Disorder Society
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