The epidemiology of generalized and focal dystonias was investigated in the Rochester, Minnesota, population over the period 1950–1982. The crude incidence of generalized dystonia was 2 per million persons per year, and for all focal dystonias combined, 24 per million per year. The crude prevalence rate was 34 per million persons for generalized dystonia and 295 per million persons for all focal dystonias. Torticollis was the most common focal dystonia; essential blepharospasm, oromandibular dystonia, spasmodic dysphonia, and writer's cramp were less common and had roughly equal incidence and prevalence rates.

References

1 Henderson JW. Essential blepharospasm. Trans Am Opthalmol Soc 1956; 54: 453–520.
2 Marsden CD. Blepharospasm-oromandibular dystonia syndrome (Brueghel's syndrome): a variant of adult onset dystonia? J Neurol Neurosurg Psychiatry 1976; 39: 1204–9.
3 Jankovic J, Ford J. Blepharospasm and orofacial-cervical dystonia: clinical and pharmacological findings in 100 patients. Ann Neurol 1983; 13: 402–11.
4 Aminoff, MJ, Dedo, HH, Izdebski K. Clinical aspects of spasmodic dysphonia. J Neurol Neurosurg Psychiatry 1978; 41: 361–5.
5 Patterson, RM, Little SC. Spasmodic torticollis. J Nerv Ment Dis 1943; 98: 571–99.
6 Matthews, WB, Beasley P, Parry-Jones W, Garland G. Spasmodic torticollis: a combined clinical study. J Neuro Neurosurg Psychiatry 1978; 41: 485–92.
7 Couch JR. Dystonia and tremor in spasmodic torticollis. Adv Neurol 1976; 14: 245–58.
8 Sheehy, MP, Marsden CD. Writer's cramp—a focal dystonia. Brain 1982; 105: 461–80.
9 Gilbert GJ. The medical treatment of spasmodic torticollis. Arch Neurol 1972; 27: 503–6.
10 Nutt, JG, Carter, JH, De Garmo, PL, Hammerstad JP. Meige syndrome and thyroid dysfunction. Neurology 1984; 34 (suppl 1): 222.
11 Thatch, BI, Chase, TN, Bosma JF. Oral facial dyskinesia associated with prolonged use of antihistaminic decongestants. N Engl J Med 1975; 293: 486–7.
12 Powers JN. Decongestant induced blepharospasm and oral facial dystonia. JAMA 1982; 247: 3244–5.
13 Jankovic, JK, Patel SC. Blepharospasm associated with brainstem lesions. Neurology 1983; 33: 1247–50.
14 Schroeder, DJ, Offord KP. A SAS Macro which utilizes local and reference population counts appropriate for incidence, prevalence, and mortality rate calculations in Rochester and Olmsted Country, Minnesota. Technical Report Series, no. 20. Rochester: Section of Medical Research Statistics, Mayo Clinic, 1982.
15 Korczyn, AD, Kahana E, Zilber N, Streiffer M, Karasso R, Alter M. Torsion dystonia in Israel. Ann Neurol 1980; 8: 387–91.
16 Lee, LV, Pascasio, FM, Fuentes, FD, Viterbo GH. Torsion dystonia in Panay, Philippines. Adv Neurol 1976; 114: 137–52.
17 Eldridge R, Gottlieb R. The primary hereditary dystonias: genetic classification of 768 families and revised estimate of gene frequency, autosomal recessive form, and selected bibliography. Adv Neurol 1976; 14: 457–74.
18 Schoenberg, BS, Anderson, DW, Haerer AF. Prevalence of Parkinson's disease in the biracial population of Copiah County, Mississippi. Neurology 1985; 35: 841–5.
19 Kurtzke, JF, Kurland LT. The epidemiology of neurologic disease. In: AB Baker, RJ Joynt, eds. Clinical Neurology. Philadelphia: Harper and Row, 1986.

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Volume3, Issue3

1988

Pages 188-194

Epidemiology of focal and generalized dystonia in Rochester, Minnesota

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Epidemiology of focal and generalized dystonia in Rochester, Minnesota

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