• Issue

    Movement Disorders: Volume 38, Issue 1

    1-157
    January 2023
Previous Issue|Next Issue
Export Citation(s)

Infographic

Free Access

January Infographic

  • First Published: 19 January 2023
January Infographic

January Infographic: Progression of Clinical and Eye Movement Markers in Preataxic Carriers of Machado-Joseph Disease

Cover Image

Free Access

Movement Disorders: Volume 38, Number 1, January 2023

  • First Published: 19 January 2023

Issue Information

Free Access

Issue Information

  • First Published: 19 January 2023

Reviewers

Thank you to Reviewers 2022

  • Pages: 1-2
  • First Published: 19 January 2023

Obituary

Free Access

Obituary for Dr. John C. Steele (1934–2022)

Huw R. Morris PhD, FRCP,  Andrew J. Lees FRCP, FRCP(Ed) F.Med.Sci, 
  • Pages: 1-3
  • First Published: 21 December 2022

Review

Open Access

(Dis-)Connected Dots in Dementia with Lewy Bodies—A Systematic Review of Connectivity Studies

Annegret Habich PhD,  Lars-Olof Wahlund MD,  Eric Westman PhD,  Thomas Dierks MD,  Daniel Ferreira PhD, 
  • Pages: 4-15
  • First Published: 17 October 2022
(Dis-)Connected Dots in Dementia with Lewy Bodies—A Systematic Review of Connectivity Studies

Dementia with Lewy bodies (DLB) is characterized by widespread connectivity disruptions compared to healthy elderly controls. Across the reviewed structural and functional neuroimaging modalities disruptions emerge most consistently in frontoparietal, default mode, and visual networks. Impairments in brain connectivity measures were associated with clinical features of DLB patients.

Viewpoint

Open Access

The Concept of Motor Reserve in Parkinson's Disease: New Wine in Old Bottles?

Merle C. Hoenig PhD,  Verena Dzialas MSc,  Alexander Drzezga MD,  Thilo van Eimeren MD, 
  • Pages: 16-20
  • First Published: 07 November 2022

Hot Topics

Identification of Novel α-Synuclein Assemblies in Lewy Body Disease

Arpine Sokratian BSc,  Hjalte Gram MSc,  Poul H. Jensen MD, PhD,  Andrew B. West PhD, 
  • Pages: 21-22
  • First Published: 14 November 2022

Nuclear Pore Complex Dysfunction in Dystonia Pathogenesis: Nucleoporins in the Spotlight

Alessio Di Fonzo MD, PhD,  Michael Zech MD, 
  • Pages: 23-24
  • First Published: 24 November 2022

Implications of DNA Methylation in Lewy Body Pathology

Benjamin Adebisi MSc,  Mohamed A. Nour MD,  María T. Periñán PhD, 
  • Pages: 25
  • First Published: 28 November 2022

Research Articles

Progression of Clinical and Eye Movement Markers in Preataxic Carriers of Machado-Joseph Disease

Camila Maria de Oliveira MD, PhD,  Vanessa Bielefeldt Leotti PhD,  Amanda Henz Cappelli MD,  Anastacia Guimarães Rocha MD,  Gabriela Ecco MD,  Gabriela Bolzan MD, PhD,  Nathalia Kersting MSc,  Maria-Luiza Saraiva-Pereira PhD,  Laura Bannach Jardim MD, PhD, 
  • Pages: 26-34
  • First Published: 21 September 2022
Progression of Clinical and Eye Movement Markers in Preataxic Carriers of Machado-Joseph Disease

January Infographic: Progression of Clinical and Eye Movement Markers in Preataxic Carriers of Machado-Joseph Disease

Open Access

Temporal Dynamics of the Scale for the Assessment and Rating of Ataxia in Spinocerebellar Ataxias

Paul Moulaire MSc,  Pierre Emmanuel Poulet MSc,  Emilien Petit MSc,  Thomas Klockgether MD,  Alexandra Durr MD, PhD,  Tetsuo Ashisawa MD,  Sophie Tezenas du Montcel MD, PhD,  for the READISCA Consortium , 
  • Pages: 35-44
  • First Published: 23 October 2022
Open Access

Progressive Spinal Cord Degeneration in Friedreich's Ataxia: Results from ENIGMA-Ataxia

Thiago J.R. Rezende PhD,  Isaac M. Adanyeguh PhD,  Filippo Arrigoni MD,  Benjamin Bender MD,  Fernando Cendes MD, PhD,  Louise A. Corben PhD,  Andreas Deistung PhD,  Martin Delatycki PhD,  Imis Dogan PhD,  Gary F. Egan PhD,  Sophia L. Göricke MD,  Nellie Georgiou-Karistianis PhD,  Pierre-Gilles Henry PhD,  Diane Hutter RN,  Neda Jahanshad PhD,  James M. Joers PhD,  Christophe Lenglet PhD,  Tobias Lindig MD,  Alberto R.M. Martinez MD, PhD,  Andrea Martinuzzi MD, PhD,  Gabriella Paparella MD,  Denis Peruzzo PhD,  Kathrin Reetz MD,  Sandro Romanzetti PhD,  Ludger Schöls,  Jörg B. Schulz MD,  Matthis Synofzik MD,  Sophia I. Thomopoulos BA,  Paul M. Thompson PhD,  Dagmar Timmann MD,  Ian H. Harding PhD,  Marcondes C. França Jr MD, PhD, 
  • Pages: 45-56
  • First Published: 29 October 2022
Open Access

Derivation and Validation of a Phenoconversion-Related Pattern in Idiopathic Rapid Eye Movement Behavior Disorder

Pietro Mattioli MD,  Beatrice Orso PsyD,  Claudio Liguori MD, PhD,  Francesco Famà BSc,  Laura Giorgetti BSc,  Andrea Donniaquio MD,  Federico Massa MD,  Andrea Giberti MD,  David Vállez García PhD,  Sanne K. Meles MD, PhD,  Klaus L. Leenders MD, PhD,  Fabio Placidi MD, PhD,  Matteo Spanetta Med Tech,  Agostino Chiaravalloti MD, PhD,  Riccardo Camedda MD,  Orazio Schillaci MD,  Francesca Izzi MD,  Nicola B. Mercuri MD,  Matteo Pardini MD, PhD,  Matteo Bauckneht MD, PhD,  Silvia Morbelli MD, PhD,  Flavio Nobili MD,  Dario Arnaldi MD, PhD, 
  • Pages: 57-67
  • First Published: 03 October 2022
Open Access

Blood Markers of Inflammation, Neurodegeneration, and Cardiovascular Risk in Early Parkinson's Disease

Michael Bartl MD,  Mohammed Dakna PhD,  Sebastian Schade MD,  Birgit Otte,  Tamara Wicke MSc,  Elisabeth Lang BSc,  Maritta Starke,  Jens Ebentheuer MD,  Sandrina Weber MD,  Karl Toischer MD,  Moritz Schnelle MD, PhD,  Friederike Sixel-Döring MD,  Claudia Trenkwalder MD,  Brit Mollenhauer MD, 
  • Pages: 68-81
  • First Published: 20 October 2022
Blood Markers of Inflammation, Neurodegeneration, and Cardiovascular Risk in Early Parkinson's Disease

Proximity Extension Assay technology applied in longitudinal plasma samples from drug-naive patients with Parkinson's disease and matched healthy control patients from the de novo Parkinson's cohort demonstrated marker candidates for state, fate, and disease progression. Reduced endothelial/atherosclerotic processes, increased thromboembolic risk, and potentially reduced α-synuclein cleavage could be validated in an independent, multicentric Parkinson Progression Marker Initiative cohort.

Open Access

Ambulatory Detection of Isolated Rapid-Eye-Movement Sleep Behavior Disorder Combining Actigraphy and Questionnaire

Andreas Brink-Kjaer PhD,  Niraj Gupta BSc,  Eric Marin MD,  Jennifer Zitser MD,  Oliver Sum-Ping MD,  Anahid Hekmat MD,  Flavia Bueno MD,  Ana Cahuas BSc,  James Langston MD,  Poul Jennum MD,  Helge B.D. Sorensen PhD,  Emmanuel Mignot MD, PhD,  Emmanuel During MD, 
  • Pages: 82-91
  • First Published: 18 October 2022
Open Access

Split-Belt Treadmill Training to Improve Gait Adaptation in Parkinson's Disease

Femke Hulzinga MSc,  Jana Seuthe PhD,  Nicholas D'Cruz PhD,  Pieter Ginis PhD,  Alice Nieuwboer PhD,  Christian Schlenstedt PhD, 
  • Pages: 92-103
  • First Published: 14 October 2022
Open Access

Practically Defined Off-State Dyskinesia Following Repeated Intraputamenal Glial Cell Line–Derived Neurotrophic Factor Administration

Katherine Lloyd MBChB, BSc,  Michael Lawton PhD,  Alan Whone FRCP, PhD, 
  • Pages: 104-112
  • First Published: 29 November 2022

Longitudinal Clinical and Biological Characteristics in Juvenile-Onset Huntington's Disease

Jordan L. Schultz PharmD,  Douglas R. Langbehn PhD,  Hend M. Al-Kaylani B.S,  Ellen van der Plas PhD,  Timothy R. Koscik PhD,  Eric A. Epping MD,  Patricia B. Espe-Pfeifer PhD,  Erin P. Martin DO,  David J. Moser PhD,  Vincent A. Magnotta PhD,  Peggy C. Nopoulos MD, 
  • Pages: 113-122
  • First Published: 01 November 2022

Suitability of Automated Writing Measures for Clinical Trial Outcome in Writer's Cramp

Noreen Bukhari-Parlakturk MD, PhD,  Michael W. Lutz PhD,  Hussein R. Al-Khalidi PhD,  Shakthi Unnithan MS,  Joyce En-Hua Wang BS,  Burton Scott MD, PhD,  Pichet Termsarasab MD,  Lawrence G. Appelbaum PhD,  Nicole Calakos MD, PhD, 
  • Pages: 123-132
  • First Published: 13 October 2022
Suitability of Automated Writing Measures for Clinical Trial Outcome in Writer's Cramp

Brief Reports

Open Access

Therapeutic Misestimation in Patients with Degenerative Ataxia: Lessons from a Randomized Controlled Trial

Roderick P.P.W.M. Maas MD,  Bart P.C. van de Warrenburg MD, PhD, 
  • Pages: 133-137
  • First Published: 19 October 2022

Increased Free Water in the Substantia Nigra in Asymptomatic LRRK2 G2019S Mutation Carriers

Dongling Zhang MD,  Liche Zhou MD,  Yuting Shi MSc,  Jun Liu MD, PhD,  Hongjiang Wei PhD,  Qiqi Tong PhD,  Hongjian He PhD,  Tao Wu MD, PhD, 
  • Pages: 138-142
  • First Published: 17 October 2022

Reduced D2/D3 Receptor Binding and Glucose Metabolism in a Macaque Model of Huntington's Disease

Alison R. Weiss PhD,  Daniele Bertoglio PhD,  William A. Liguore MPH,  Kristin Brandon BS,  John Templon BS,  Jeanne Link PhD,  Jodi L. McBride PhD, 
  • Pages: 143-147
  • First Published: 21 December 2022

In Vivo 18F-Florzolotau Tau Positron Emission Tomography Imaging in Parkinson's Disease Dementia

Yilin Tang MD,  Ling Li PhD,  Tianyu Hu MD,  Fangyang Jiao PhD,  Linlin Han PhD,  Shiyu Li MD,  Zhiheng Xu MD,  Yun Fan PhD,  Yimin Sun PhD,  Fengtao Liu MD,  Tzu-Chen Yen MD, PhD,  Chuantao Zuo MD, PhD,  Jian Wang MD, PhD, 
  • Pages: 147-152
  • First Published: 11 November 2022

Letters: New Observations

Open Access

Salivary α-Synuclein RT-QuIC Correlates with Disease Severity in de novo Parkinson's Disease

Giorgio Vivacqua MD, PhD,  Matthew Mason MSc,  Maria Ilenia De Bartolo MD,  Michal Węgrzynowicz PhD,  Laura Calò PhD,  Daniele Belvisi MD, PhD,  Antonio Suppa MD, PhD,  Giovanni Fabbrini MD,  Alfredo Berardelli MD,  MariaGrazia Spillantini PhD, 
  • Pages: 153-155
  • First Published: 19 October 2022
Open Access

Both Heterozygous and Homozygous Loss-of-Function JPH3 Variants Are Associated with a Paroxysmal Movement Disorder

Dora Steel BMBCh,  Aikaterini Vezyroglou MD,  Katy Barwick PhD,  Martin Smith MBBS,  Julie Vogt MD,  Frances M. Gibbon MB, ChB,  J. Helen Cross PhD,  Manju A. Kurian PhD, 
  • Pages: 155-157
  • First Published: 23 October 2022